Nobel winning biologist Rita Levi-Montalcini dies

Rita Levi-Montalcini, a biologist who conducted underground research in defiance of Fascist persecution and went on to win a Nobel Prize for helping unlock the mysteries of the cell, died at her home in Rome on Sunday.

She was 103 and had worked well into her final years, the Associated Press reported.

Rome Mayor Gianni Alemanno, announcing her death in a statement, called it a great loss "for all of humanity." He praised her as someone who represented "civic conscience, culture and the spirit of research of our time."

Italy's so-called "Lady of the Cells," a Jew who lived through anti-Semitic discrimination and the Nazi invasion, became one of her country's leading scientists and shared the Nobel medicine prize in 1986 with American biochemist Stanley Cohen for groundbreaking research carried out in the United States. Her research increased the understanding of many conditions, including tumors, developmental malformations and senile dementia.

A petite woman with upswept white hair, she kept an intensive work schedule well into old age. "At 100, I have a mind that is superior — thanks to experience — than when I was 20," she said in 2009.

"A beacon of life is extinguished" with her death, said a niece, Piera Levi-Montalcini, who is a city councilwoman in Turin. She told the Turin daily newspaper La Stampa that her aunt passed away peacefully "as if sleeping" after lunch and that the scientist had kept up her research studies several hours a day "right up until the end."